Fused-Core particle technology has been thoroughly studied by recognized experts in the field of chromatography. Below is a partial list of their publications that report on the characteristics, performance, and application of UHPLC columns packed with Fused-Core particles.

1. Mass-transfer kinetics in a shell packing material for chromatography. Anal. Chem (2007) 79, 5972-5979, Cavazzini, A., Gritti, F., Kaczmarski, K., Marchetti, N. & Guiochon, G.

2. Fused core particle technology as an alternative to sub 2 m particles to achieve high separation efficiency with low backpressure. Journal of separation science (2007) 30, 3104-3109, Cunliffe, J. & Maloney, T.

3. Comparison between the efficiencies of columns packed with fully and partially porous C18-bonded silica materials. Journal of Chromatography A (2007) 1157, 289-303, Gritti, F., Cavazzini, A., Marchetti, N. & Guiochon, G.

4. Unusual behavior of the height equivalent to a theoretical plate of a new poroshell stationary phase at high temperatures. Journal of Chromatography A (2007) 1169, 125-138, Gritti, F. & Guiochon, G.

5. Comparative study of the performance of columns packed with several new fine silica particles: Would the external roughness of the particles affect column properties? Journal of Chromatography A (2007) 1166, 30-46, Gritti, F. & Guiochon, G.

6. Comparison between the loading capacities of columns packed with partially and totally porous fine particles:: What is the effective surface area available for adsorption? Journal of Chromatography A (2007) 1176, 107-122, Gritti, F. & Guiochon, G.

7. Fused-core silica column high-performance liquid chromatography/tandem mass spectrometric determination of rimonabant in mouse plasma. Anal. Chem (2007) 79, 5668-5673, Hsieh, Y., Duncan, C. & Brisson, J.

8. Modeling of the mass-transfer kinetics in chromatographic columns packed with shell and pellicular particles. Anal. Chem (2007) 79, 4648-4656, Kaczmarski, K. & Guiochon, G.

9. Fused core particles for HPLC columns. American laboratory (2007) 39, 18-21, Kirkland, J., Langlois, T. & DeStefano, J.

10. New Chromatography Columns and Accessories at Pittcon 2007: Part I. LC GC North America (2007) March, 248-266, Majors, R. E.

11. Gradient elution separation and peak capacity of columns packed with porous shell particles. Journal of Chromatography A (2007) 1163, 203-211, Marchetti, N., Cavazzini, A., Gritti, F. & Guiochon, G.

12. High peak capacity separations of peptides in reversed-phase gradient elution liquid chromatography on columns packed with porous shell particles. Journal of Chromatography A (2007) 1176, 206-216, Marchetti, N. & Guiochon, G.

13. Kinetic plot method as a tool to design coupled column systems producing 100,000 theoretical plates in the shortest possible time. Journal of Chromatography A (2008) 1212, 23-34, Cabooter, D., Lestremau, F., Lynen, F., Sandra, P. & Desmet, G.

14. Determination of zearalenone and its metabolites in urine samples by liquid chromatography with electrochemical detection using a carbon nanotube-modified electrode. Journal of Chromatography A (2008) 1212, 54-60, De Andres, F., Zougagh, M., Casta eda, G. & Ríos, A.

15. Characteristics of Superficially-Porous Silica Particles for Fast HPLC: Some Performance Comparisons with Sub-2-m Particles. Journal of chromatographic science (2008) 46, 254-260, DeStefano, J., Langlois, T. & Kirkland, J.

16. Surface Area of Reversed-Phase HPLC Columns. Analytical chemistry (2008) 80, 6358-6364, Giaquinto, A., Liu, Z., Bach, A. & Kazakevich, Y.

17. Implementations of two-dimensional liquid chromatography. Journal of Chromatography A (2008) 1189, 109-168, Guiochon, G., Marchetti, N., Mriziq, K. & Shalliker, R.

18. Serial coupled columns reversed-phase separations in high-performance liquid chromatography:: Tool for analysis of complex real samples. Journal of Chromatography A (2008) 1188, 208-215, Herrero, M., Cacciola, F., Donato, P., Giuffrida, D., Dugo, G., Dugo, P. & Mondello, L.

19. RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model. Journal of Proteome Research (2008) 7, 4982-4991, Hu, C., van Dommelen, J., van der Heijden, R., Spijksma, G., Reijmers, T., Wang, M., Slee, E., Lu, X., Xu, G. & van der Greef, J.

20. High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometry for the detection of 17alpha-ethinylestradiol in hepatocytes. Journal of Chromatography B (2008) 870, 186-191, Li, F., Hsieh, Y. & Korfmacher, W.

21. Evaluation of the properties of a superficially porous silica stationary phase in hydrophilic interaction chromatography. Journal of Chromatography A (2008) 1193, 85-91, McCalley, D.

22. Estimation of the extent of the water-rich layer associated with the silica surface in hydrophilic interaction chromatography. Journal of Chromatography A (2008) 1192, 225-229, McCalley, D. & Neue, U.

23. Determination of fatty alcohol ethoxylates by derivatization with phthalic anhydride followed by liquid chromatography with UV-vis detection. Journal of Chromatography A (2008) 1203, 47-53, Micó-Tormos, A., Simó-Alfonso, E. & Ramis-Ramos, G.

24. Synthesis, Structure- Activity Relationships, and Biological Profiles of a Quinazolinone Class of Histamine H3 Receptor Inverse Agonists. Journal of medicinal chemistry (2008) 51, 4780-4789, Nagase, T., Mizutani, T., Ishikawa, S., Sekino, E., Sasaki, T., Fujimura, T., Ito, S., Mitobe, Y., Miyamoto, Y. & Yoshimoto, R.

25. Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists. J. Med. Chem (2008) 51, 6889-6901, Nagase, T., Mizutani, T., Sekino, E., Ishikawa, S., Ito, S., Mitobe, Y., Miyamoto, Y., Yoshimoto, R., Tanaka, T. & Ishihara, A.

26. Fused-core particles: a practical alternative to sub-2 micron particles. Journal of chromatographic science (2008) 46, 883-886, Salisbury, J.

27. What is “Hot” in Column Technologies for Liquid Chromatography? American laboratory (2008) 40, 13-17, Svec, F.

28. Particle packed columns and monolithic columns in high-performance liquid chromatography-comparison and critical appraisal. Journal of Chromatography A (2008) 1184, 393-415, Unger, K., Skudas, R. & Schulte, M.

29. Radial heterogeneity of some analytical columns used in high-performance liquid chromatography. Journal of Chromatography A (2009) 1216, 3185-3191, Abia, J., Mriziq, K. & Guiochon, G.

30. Application of a Dried-DMSO rapid throughput 24-h equilibrium solubility in advancing discovery candidates. European Journal of Pharmaceutical Sciences (2009) 37, 172-182, Alelyunas, Y., Liu, R., Pelosi-Kilby, L. & Shen, C.

31. Comprehensive two-dimensional liquid chromatography separations of pharmaceutical samples using dual Fused-Core columns in the 2nd dimension. Journal of Chromatography A (2009) 1216, 1338-1345, Alexander, A. & Ma, L.

32. Looking Beyond the Column: An Investigation into Method Irreproducibility for an Active Pharmaceutical Ingredient. Chromatographia (2009) 70, 1561-1567, Bernardoni, F., Sajonz, P., Zang, J., Lee, C., Marcinko, S., Abrahim, A. & Helmy, R.

33. Fused core, sub 2 um packings, and monolithic HPLC columns: a comparative evaluation. Journal of separation science (2009) 32, 2723-2731, Brice, R., Zhang, X. & Colón, L.

34. A high-throughput LC-MS/MS method for the quantitation of posaconazole in human plasma: Implementing fused core silica liquid chromatography. Journal of pharmaceutical and biomedical analysis (2009) 50, 46-52, Cunliffe, J., Noren, C., Hayes, R., Clement, R. & Shen, J.

35. Approaches to comprehensive multidimensional liquid chromatography systems. Journal of Chromatography A (2009) 1216, 1363-1371, Fairchild, J., Horváth, K. & Guiochon, G.

36. Tryptic digest analysis by comprehensive reversed phase× two reversed phase liquid chromatography (RP LC× 2RP LC) at different pH's. Journal of separation science (2009) 32, 1137-1144, François, I., Cabooter, D., Sandra, K., Lynen, F., Desmet, G. & Sandra, P.

37. Semi automated tandem mass spectrometric (MS/MS) triple quadrupole operating parameter optimization for high throughput MS/MS detection workflows. Rapid Communications in Mass Spectrometry (2009) 23, 1303-1312, Geddes, K., Adamson, G., Dube, N., Crathern, S. & King, R.

38. Comparison of molecularly imprinted, mixed-mode and hydrophilic balance sorbents performance in the solid-phase extraction of amphetamine drugs from wastewater samples for liquid chromatography-tandem mass spectrometry determination. Journal of Chromatography A (2009) 1216, 8435-8441, González-Mariño, I., Quintana, J., Rodríguez, I., Rodil, R., González-Peñas, J. & Cela, R.

39. Peak shapes of acids and bases under overloaded conditions in reversed-phase liquid chromatography, with weakly buffered mobile phases of various pH: A thermodynamic interpretation. Journal of Chromatography A (2009) 1216, 63-78, Gritti, F. & Guiochon, G.

40. Adsorption mechanism of acids and bases in reversed-phase liquid chromatography in weak buffered mobile phases designed for liquid chromatography/mass spectrometry. Journal of Chromatography A (2009) 1216, 1776-1788, Gritti, F. & Guiochon, G.

41. Evaluation of The Peak Capacity of Various RP-Columns for Small Molecule Compounds in Gradient Elution. Chromatographia (2009) 70, 1045-1054, Guo, Y., Srinivasan, S. & Gaiki, S.

42. Optimization strategies for off-line two-dimensional liquid chromatography. Journal of Chromatography A (2009) 1216, 2511-2518, Horváth, K., Fairchild, J. & Guiochon, G.

43. Hydrophilic interaction liquid chromatography/tandem mass spectrometry for the simultaneous determination of dasatinib, imatinib and nilotinib in mouse plasma. Rapid Communications in Mass Spectrometry (2009) 23, 1364-1370, Hsieh, Y., Galviz, G., Zhou, Q. & Duncan, C.

44. Analysis of impurities in streptomycin and dihydrostreptomycin by hydrophilic interaction chromatography/electrospray ionization quadrupole ion trap/time of flight mass spectrometry. Rapid Communications in Mass Spectrometry (2009) 23, 907-914, Kawano, S.

45. Characterization of the alcoholic fraction of vegetable oils by derivatization with diphenic anhydride followed by high-performance liquid chromatography with spectrophotometric and mass spectrometric detection. Journal of Chromatography A (2009) 1216, 230-236, Lerma-García, M., Ramis-Ramos, G., Herrero-Martínez, J., Gimeno-Adelantado, J. & Simó-Alfonso, E.

46. Equation for Peak Capacity Estimation in Two-Dimensional Liquid Chromatography. Analytical chemistry (2009) 81, 845-850, Li, X., Stoll, D. & Carr, P.

47. Chromatographic and spectroscopic studies on the chiral recognition of sulfated [beta]-cyclodextrin as chiral mobile phase additive:: Enantiomeric separation of a chiral amine. Journal of Chromatography A (2009) 1216, 1232-1240, Ma, S., Shen, S., Haddad, N., Tang, W., Wang, J., Lee, H., Yee, N., Senanayake, C. & Grinberg, N.

48. Determination of fatty alcohol ethoxylates with diphenic anhydride derivatization and liquid chromatography with spectrophotometric detection:: A comparative study with other anhydrides. Journal of Chromatography A (2009) 1216, 3023-3030, Micó-Tormos, A., Bianchi, F., Simó-Alfonso, E. & Ramis-Ramos, G.

49. A review of current trends and advances in modern bio-analytical methods: Chromatography and sample preparation. Analytica chimica acta (2009) 656, 8-35, Nováková, L. & Vlcková, H.

50. Comparison of fused-core and conventional particle size columns by LC-MS/MS and UV: Application to pharmacokinetic study. Journal of pharmaceutical and biomedical analysis (2009) 50, 491-500, Song, W., Pabbisetty, D., Groeber, E., Steenwyk, R. & Fast, D.

51. Reductive Amination of Aldehyde 2, 4-Dinitorophenylhydrazones Using 2-Picoline Borane and High-Performance Liquid Chromatographic Analysis. Analytical chemistry (2009) 81, 485-489, Uchiyama, S., Inaba, Y., Matsumoto, M. & Suzuki, G.

52. Analysis of human antibody IgG2 domains by reversed-phase liquid chromatography and mass spectrometry Journal of Chromatography B (2009) 877, 1613-1620, Yan, B., Eris, T., Yates, Z., Hong, R. W., Steen, S., Kleemann, G., Wang, W. & Liu, J. L.

53. Critical comparison of performances of superficially porous particles and sub-2 [mu] m particles under optimized ultra-high pressure conditions. Journal of Chromatography A (2009) 1216, 4597-4605, Zhang, Y., Wang, X., Mukherjee, P. & Petersson, P.

54. Comparison study of porous, fused-core, and monolithic silica-based C18 HPLC columns for Celestoderm-V Ointment® analysis. Journal of pharmaceutical and biomedical analysis (2009) 50, 815-822, Zheng, J., Patel, D., Tang, Q., Markovich, R. & Rustum, A.

55. A high throughput dried DMSO Log D lipophilicity measurement based on 96-well shake-flask and atmospheric pressure photoionization mass spectrometry detection. Journal of Chromatography A (2010) 1217, 1950-1955, Alelyunas, Y., Pelosi-Kilby, L., Turcotte, P., Kary, M. & Spreen, R.

56. Halo Columns: New Generation Technology for High Speed Liquid Chromatography. Journal of chromatographic science (2010) 48, 386-394, Ali, I., Gaitonde, V. & Grahn, A.

57. How well does urinary lyso-Gb3 function as a biomarker in Fabry disease? Clinica Chimica Acta (2010) 411, 1906-1914, Auray-Blais, C., Ntwari, A., Clarke, J., Warnock, D., Oliveira, J., Young, S., Millington, D., Bichet, D., Sirrs, S. & West, M.

58. Physical characterization and evaluation of HPLC columns packed with superficially porous particles. Journal of separation science (2010) 33, 2547-2557, Baker, J., Vinci, J., Moore, A. & Colón, L.

59. The kinetic plot method applied to gradient chromatography: theoretical framework and experimental validation. Journal of Chromatography A (2010) 1217, 2787-2795, Broeckhoven, K., Cabooter, D., Lynen, F., Sandra, P. & Desmet, G.

60. Relationship between the Particle Size Distribution of Commercial Fully Porous and Superficially Porous High-Performance Liquid Chromatography Column Packings and their Chromatographic Performance. Journal of Chromatography A (2010) 1217, 7074-7081, Cabooter, D., Fanigliulo, A., Bellazzi, G. & Allieri, B.

61. Efficiency of the same neat silica column in hydrophilic interaction chromatography and per aqueous liquid chromatography. Journal of Chromatography A (2010) 1217, 683-688, Gritti, F., dos Santos Pereira, A., Sandra, P. & Guiochon, G.

62. Physical properties and structure of fine core-shell particles used as packing materials for chromatography:: Relationships between particle characteristics and column performance. Journal of Chromatography A (2010) 1217, 3819-3843, Gritti, F., Leonardis, I., Abia, J. & Guiochon, G.

63. New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches. Analytical and Bioanalytical Chemistry (2010) 397, 1069-1082, Guillarme, D., Ruta, J., Rudaz, S. & Veuthey, J.

64. Comparison of the mass transfer in totally porous and superficially porous stationary phases in liquid chromatography. Analytical and Bioanalytical Chemistry (2010) 397, 1307-1314, Kiss, I., Bacskay, I., Kilár, F. & Felinger, A.

65. Extension of the C18 stationary phase knowledge by using the carotenoid test. Journal of separation science (2010) 33, 3097-3105, Lesellier, E.

66. Widespread but small-scale changes in the structural and dynamic properties of vaccinia virus poly (A) polymerase upon association with its processivity factor in solution. Biochemistry (2010) 49, 6247-6262, Li, C., Koter, M., Ye, X., Zhou, S., Chou, W., Luo, R. & Gershon, P.

67. Dissipation and Residues Detection of Dioctyldiethylenetriamine Cetate in Rice Plant and Environment by QuEChERS Method and Liquid Chromatography/Electrospray Tandem Mass Spectrometry. Bulletin of environmental contamination and toxicology (2010) 84, 596-601, Li, X., Jiang, Y., Shan, W. & Pan, C.

68. A quantitative investigation of fucosylated serum glycoproteins with application to esophageal adenocarcinoma. Electrophoresis (2010) 31, 1833-1841, Mann, B., Madera, M., Klouckova, I., Mechref, Y., Dobrolecki, L., Hickey, R., Hammoud, Z. & Novotny, M.

69. Instrumental considerations for the effective operation of short, highly efficient fused-core columns. Investigation of performance at high flow rates and elevated temperatures. Journal of Chromatography A (2010) 1217, 4561-4567, McCalley, D.

70. The use of charged aerosol detection with HPLC for the measurement of lipids. Lipidomics, Methods in Molecular Biology (2010) 579, 469-482, Plante, M., Bailey, B. & Acworth, I.

71. The Impact of Sampling Time on Peak Capacity and Analysis Speed in On-line Comprehensive Two-Dimensional Liquid Chromatography. Journal of Chromatography A (2010) 1217, 5700-5709, Potts, L., Stoll, D., Li, X. & Carr, P.

72. Subcellular distribution of okadaic acid in the digestive gland of Mytilus galloprovincialis: First evidences of lipoprotein binding to okadaic acid. Toxicon (2010) 55, 221-226, Rossignoli, A. & Blanco, J.

73. Wider Pore Superficially Porous Particles for Peptide Separations by HPLC. Journal of chromatographic science (2010) 48, 566-571, Schuster, S., Wagner, B., Boyes, B. & Kirkland, J.

74. Optimization and validation of a high performance liquid chromatography method for rapid determination of sinafloxacin, a novel fluoroquinolone in rat plasma using a fused-core C18-silica column. Journal of pharmaceutical and biomedical analysis (2010) 51, 889-893, Wang, S., Wen, J., Cui, L., Zhang, X., Wei, H., Xie, R., Feng, B., Wu, Y. & Fan, G.